abstract：:Mice lacking myostatin (GDF-8), a negative regulator of skeletal muscle growth, show a significant increase in muscle mass versus normal mice. We compared wild-type and myostatin deficient mice to assess the postnatal effect of elevated masticatory loads due to increased jaw-adductor muscle activity and greater bite f...

journal_title：Archives of oral biology

authors： Nicholson EK,Stock SR,Hamrick MW,Ravosa MJ

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVE:The function of apoptosis and its regulation in odontoblasts remain unclear. In this study, we characterize the possible role of transforming growth factor (TGF)-beta 1 in the induction of apoptosis and the molecular mechanisms that mediate TGF-beta1-induced apoptosis in odontoblasts. METHODS:Annexin V/propi...

journal_title：Archives of oral biology

authors： He WX,Niu ZY,Zhao SL,Smith AJ

更新日期：2005-11-01 00:00:00

abstract：:The neuropeptide contents of rat salivary glands were increased four weeks after sympathetic postganglionic denervation (but not after preganglionic denervation): calcitonin gene-related peptide (CGRP) by 400 and 65% in the parotid and submandibular glands, respectively; substance P by 30% in the submandibular gland; ...

journal_title：Archives of oral biology

authors： Ekström J,Ekman R

更新日期：2005-10-01 00:00:00

abstract：:Tissue transglutaminase (TGase 2) has been implicated in numerous cellular functions, i.e., apoptosis, differentiation, extracellular matrix protein cross-linking and organogenesis. Earlier report of the strong transient expression of TGase 2 localized at the anchoring sites of muscle bundles of human embryo and recen...

journal_title：Archives of oral biology

authors： Lee SK,Kim YS,Lee SS,Lee YJ,Song IS,Park SC,Chi JG,Chung SI

更新日期：2005-09-01 00:00:00

abstract：UNLABELLED:Tooth enamel is formed by ameloblasts, which are derived from the epithelial cells of the enamel organ. OBJECTIVE:The purpose of this study was to grow human ameloblast-like epithelial cells in culture. DESIGN:Human fetal tooth organs were isolated, and the cells were separated by digestion in collagenase/...

journal_title：Archives of oral biology

authors： DenBesten PK,Machule D,Zhang Y,Yan Q,Li W

更新日期：2005-08-01 00:00:00

abstract：:Garlic (Allium sativum) has long been known to have antibacterial, antifungal and antiviral properties but there are few data on its effects against oral bacterial species particularly putative periodontal pathogens or their enzymes. Filter sterilised, aqueous extract of garlic was tested for ability to inhibit the gr...

journal_title：Archives of oral biology

authors： Bakri IM,Douglas CW

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVES:To analyse age- and gender-related microscopic changes in sublingual glands obtained from human cadavers. STUDY DESIGN:One hundred eighty six human sublingual glands were obtained from 93 autopsies. Approximately five individuals of each gender per decade of life were allocated to three age groups: group I ...

journal_title：Archives of oral biology

authors： Azevedo LR,Damante JH,Lara VS,Lauris JR

更新日期：2005-06-01 00:00:00

abstract：:Ascorbic acid (AA), also known as Vitamin C, is a cofactor required for the function of several hydroxylases. It is not synthesised in humans and has to be provided by diet. Its absence is responsible for scurvy, a condition related to the defective synthesis of collagen by the reduced function of prolylhydroxylase. A...

journal_title：Archives of oral biology

authors： Carinci F,Pezzetti F,Spina AM,Palmieri A,Laino G,De Rosa A,Farina E,Illiano F,Stabellini G,Perrotti V,Piattelli A

更新日期：2005-05-01 00:00:00

abstract：:Aim of the in situ-study was to evaluate fluoride retention in sound and demineralised enamel after application of a novel water-based fluoride (0.12% F) varnish Mirafluorid (Hager and Werken, Germany) compared to the resin-based varnish (2.26% F) Duraphat (Colgate, USA). Each five enamel specimens were prepared from ...

journal_title：Archives of oral biology

authors： Attin T,Grieme R,Paqué F,Hannig C,Buchalla W,Attin R

更新日期：2005-03-01 00:00:00

abstract：:Notch receptors are involved in cell fate decisions through the process of lateral inhibition or inductive signalling. Jagged2 belongs to the family of transmembrane proteins that serve as the ligands for Notch receptors. We have analysed the expression of the Jagged2 gene in developing mouse teeth. Jagged2 expression...

journal_title：Archives of oral biology

authors： Mitsiadis TA,Regaudiat L,Gridley T

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVE:To what extent is the current knowledge about regulatory and patterning processes gained from research on animal models (predominantly mouse) applicable to describe certain aspect of human prenatal dental development? METHODS:3D-reconstructions were produced from serial sections of human dental primordia (Ra...

journal_title：Archives of oral biology

authors： Radlanski RJ,Renz H

更新日期：2005-02-01 00:00:00

abstract：:Apatite crystal growth rate and morphology in mineralized tissues are considered to be controlled by surface interaction with extracellular matrix proteins. During enamel maturation where protein is finally removed from crystal surfaces to permit massive crystal growth, pH oscillates between approximately 5.8 and appr...

journal_title：Archives of oral biology

authors： Robinson C,Connell S,Brookes SJ,Kirkham J,Shore RC,Smith DA

更新日期：2005-02-01 00:00:00

abstract：:The aim of this study was to test the hypothesis that hypoxia and interleukin-1 (IL-1)beta played a substantial role in gene expressions of matrix metalloproteinases (MMPs) in temporomandibular joint (TMJ) disc cells. The TMJ disc cells were isolated from rabbit TMJ, and cultured in Dulbecco's modified Eagle's medium ...

journal_title：Archives of oral biology

authors： Yamaguchi A,Tojyo I,Yoshida H,Fujita S

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:Changes in the masticatory function of ferrets have been shown to cause alterations in their craniofacial morphology. The aim of the present study was to investigate how the functional changes influence the histochemical characteristics of fibres of the masticatory muscles of the animal. DESIGN:Forty five-we...

journal_title：Archives of oral biology

authors： He T,Olsson S,Daugaard JR,Kiliaridis S

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVE:Assess the applicability of ion chromatography (IC) for human saliva studies. MATERIALS AND METHODS:The behaviour of an ion chromatograph (DX-100, Dionex) in the analysis of human saliva was examined in the following respects: calibration, reproducibility, recovery, and effect of pre-treatment conditions (di...

journal_title：Archives of oral biology

authors： Chen ZF,Darvell BW,Leung VW

更新日期：2004-11-01 00:00:00

abstract：:After an initial demineralisation, an intensive fluoridation is capable of inhibiting the erosive mineral loss in dentine completely, which might be related to the presence of the exposed organic dentine matrix. Aim of the present study was, therefore, to evaluate whether fluoride is also effective when the organic ma...

journal_title：Archives of oral biology

authors： Ganss C,Klimek J,Starck C

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVE:Neurotrophin-3 (NT-3) is known to ameliorate central changes that result from peripheral nerve injury and may promote regeneration of myelinated axons. We have assessed its role in the functional recovery of sensory afferents and autonomic efferents after repair of the chorda tympani and lingual nerves in the...

journal_title：Archives of oral biology

authors： Robinson PP,Yates JM,Smith KG

更新日期：2004-10-01 00:00:00

abstract：:Actinomyces species are predominant early colonizers of the oral cavity and prime mediators of inter-bacterial adhesion and coaggregation. Previous workers have evaluated the adhesion of Actinomyces spp. by quantitative assessment of sessile, as opposed to planktonic cells attached to substrates, but did not quantify ...

journal_title：Archives of oral biology

authors： Tang G,Yip HK,Samaranayake LP,Chan KY,Luo G,Fang HH

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to compare tooth components (enamel and dentin) in Familial Dysautonomia (FD) and Down syndrome (DS) in order to assess the extent to which each was affected. DESIGN:The design was cross-sectional. The sample consisted of 20 FD patients and 45 DS patients. The control group comp...

journal_title：Archives of oral biology

authors： Zilberman U,Patricia S,Kupietzky A,Mass E

更新日期：2004-08-01 00:00:00

abstract：UNLABELLED:Growth hormone (GH) stimulates mandibular growth but its effect on the mandibular condylar cartilage is not well understood. OBJECTIVE:This study was designed to understand the influence of GH on mitotic activity and on chondrocytes maturation. The effect of GH on cartilage thickness was also determined. D...

journal_title：Archives of oral biology

authors： Ramirez-Yañez GO,Young WG,Daley TJ,Waters MJ

更新日期：2004-07-01 00:00:00

abstract：:Genetic studies have recently identified a mutation of one allele of runt-related gene 2 (RUNX2/CBFA1) as the cause for an autosomal-dominant skeletal disorder, cleidocranial dysplasia (CCD), which is characterised by hypoplasia of the clavicles and calvariae and widened sutures and fontanelles. In addition, CCD is fr...

journal_title：Archives of oral biology

authors： Yoda S,Suda N,Kitahara Y,Komori T,Ohyama K

更新日期：2004-06-01 00:00:00

abstract：:Micelles represent macromolecular structures in saliva and the aim of this study was to identify salivary proteins that occur in these globular particles. Micelles were isolated from whole saliva (WS) collected from three individuals and analysed in different experiments. Samples were subjected to polyacrylamide gel e...

journal_title：Archives of oral biology

authors： Soares RV,Lin T,Siqueira CC,Bruno LS,Li X,Oppenheim FG,Offner G,Troxler RF

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE:To determine if local, gingival crevicular fluid (GCF) levels of TGFbeta1 were altered in drug-induced gingival overgrowth. PATIENTS AND METHODS:GCF samples were collected on Periopaper strips from 45 renal transplant recipients who had been medicated with cyclosporin or cyclosporin in combination with other...

journal_title：Archives of oral biology

authors： Wright HJ,Chapple IL,Blair F,Matthews JB

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE:We previously proposed the hamster cheek pouch model of oral cancer for BNCT studies. We herein present the biodistribution of a non-toxic boron compound, GB-10 (Na(2)(10)B10H10), in this model to assess its potential for BNCT or BNCT enhanced Fast Neutron Therapy. MATERIALS AND METHODS:We evaluated the upta...

journal_title：Archives of oral biology

authors： Heber E,Trivillin VA,Nigg D,Kreimann EL,Itoiz ME,Rebagliati RJ,Batistoni D,Schwint AE

更新日期：2004-04-01 00:00:00

abstract：:In the majority of studies on masticatory performance, the degree of food breakdown has been determined by sieving the food with one or more sieves. The aim of the present study was to compare the results obtained with a single and a multiple sieve method, as these methods have never been compared. We analysed the che...

journal_title：Archives of oral biology

authors： van der Bilt A,Fontijn-Tekamp FA

更新日期：2004-03-01 00:00:00

abstract：:In the majority of studies on masticatory performance, the degree of food breakdown has been determined by sieving the food with one or more sieves. The aim of the present study was to compare the results obtained with a single and a multiple sieve method, as these methods have never been compared. We analysed the che...

journal_title：Archives of oral biology

authors： van der Bilt A,Fontijn-Tekamp FA

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVE:Eight commercially available resins, Epoxy Embedding Medium ("Epon"), Spurr, Epofix, Epo-Kwick, Epo-Thin, Technovit 9100 New, Unicryl, and Vestopal W, all intended for embedding specimens for microscopy, were tested and compared for binding and adaptation to the enamel surface of human third molar crowns that...

journal_title：Archives of oral biology

authors： Li C,Risnes S

更新日期：2004-01-01 00:00:00

abstract：:Candidal adherence to mucosal surfaces is considered as the first step in the pathogenesis of oral candidiasis. We examined the effect of antifungal polyenes, amphotericin B, nystatin and natamycin, at sublethal and minimum inhibitory concentrations (MICs) on the adherence of Candida albicans and Candida glabrata to H...

journal_title：Archives of oral biology

authors： Dorocka-Bobkowska B,Konopka K,Düzgüneş N

更新日期：2003-12-01 00:00:00

abstract：:This study examined the expression of MMP-2 and MMP-9 in normal and human malignant oral keratinocytes. The expression of pro-MMP-2 and pro-MMP-9 was heterogeneous in the malignant cell lines. Normal oral keratinocytes expressed less pro-MMP-2 and more pro-MMP-9 than their malignant counterparts. Cells that expressed ...

journal_title：Archives of oral biology

authors： Robinson CM,Stone AM,Shields JD,Huntley S,Paterson IC,Prime SS

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVE:To understand bone regeneration process after tooth extraction could be a clue to develop a new strategy for alveolar bone reconstruction. Recently, accumulated evidences support that connective tissue growth factor (CTGF) is implicated in tissue repair of many tissues. In this study, we investigated the spat...

journal_title：Archives of oral biology

authors： Kanyama M,Kuboki T,Akiyama K,Nawachi K,Miyauchi FM,Yatani H,Kubota S,Nakanishi T,Takigawa M

更新日期：2003-10-01 00:00:00

abstract：:Destrin, an actin-binding protein, is partly phosphorylated at Ser-2 (numbering on the matured form) in the resting rat parotid gland, and beta-adrenergic or cholinergic stimulation of this gland induces its dephosphorylation. In this study, we searched for the protein kinase involved in phosphorylation of destrin. We...

journal_title：Archives of oral biology

authors： Nakano S,Kanamori T,Suzuki M,Titani K

更新日期：2003-09-01 00:00:00

abstract：:An immunofluorescence study of the expression of keratin 14 (K14) during the formation of filiform papillae was performed and the progress of keratinization of the epithelium of the rat tongue was monitored on semi-ultrathin sections by laser-scanning microscopy. Differential interference contrast (DIC) images were al...

journal_title：Archives of oral biology

authors： Iwasaki S,Aoyagi H,Yoshizawa H

更新日期：2003-08-01 00:00:00

abstract：:Histatins 1, 3 and 5 are the major members of a histidine-rich protein family present in human salivary secretions. These proteins are distinct from many salivary proteins in their high positive charge density at neutral pH, and their antibacterial and antifungal properties. In this study, the hydroxyapatite adsorptio...

journal_title：Archives of oral biology

authors： Yin A,Margolis HC,Grogan J,Yao Y,Troxler RF,Oppenheim FG

更新日期：2003-05-01 00:00:00

abstract：:Langerhans cells (LC) are dendritic cells of the immune system able to capture intraepithelial pathogens and migrate to regional lymph nodes to present them to naive T cells. Up to now immunohistological studies on human gingival LC have been carried out using antibodies against HLA-DR or CD1a molecules. A new marker ...

journal_title：Archives of oral biology

authors： Séguier S,Bodineau A,Godeau G,Pellat B,Brousse N

更新日期：2003-04-01 00:00:00

abstract：:Boron Neutron Capture Therapy (BNCT) is a bimodal cancer treatment based on the selective accumulation of 10B in tumors and concurrent irradiation with thermalized neutrons. The short-range, high-LET radiation produced by the capture of neutrons by 10B could potentially control tumor while sparing normal tissue if the...

journal_title：Archives of oral biology

authors： Kreimann EL,Miura M,Itoiz ME,Heber E,Garavaglia RN,Batistoni D,Rebagliati RJ,Roberti MJ,Micca PL,Coderre JA,Schwint AE

更新日期：2003-03-01 00:00:00

abstract：:Sample groups of children (n=50) and adults (n=38) were selected from pools of 207 children, (11-13-year olds from two primary schools) and 94 adults (25-44-year olds from four governmental agencies) who were the subjects of an oral health survey among Tibetans living in Lhasa, Tibet Autonomous Region. Mean ages of th...

journal_title：Archives of oral biology

authors： Leung WK,Yau JY,Cheung BP,Jin LJ,Zee KY,Lo EC,Samaranayake LP,Corbet EF

更新日期：2003-02-01 00:00:00

abstract：:Exposure to high fluoride concentrations in the immediate environment of the tissue is recognized to result in the post-translational modification of non-collagenous dentine extracellular matrix (ECM) components, potentially altering dentine mineralization. However, less is known about the effects of fluoride exposure...

journal_title：Archives of oral biology

authors： Moseley R,Sloan AJ,Waddington RJ,Smith AJ,Hall RC,Embery G

更新日期：2003-01-01 00:00:00

abstract：:In a previous study, it was shown that tooth germs of neonatal homozygous parathyroid hormone-related protein (PTHrP)-knockout mice are penetrated or compressed by the surrounding alveolar bone, suggesting an important role for PTHrP in the formation and activation of osteoclasts around growing tooth germs. In order t...

journal_title：Archives of oral biology

authors： Mekaapiruk K,Suda N,Hammond VE,Beck F,Kuroda T,Takano Y,Terashima T

更新日期：2002-09-01 00:00:00

abstract：:Substituting ferrets for rats and dogs as animal models for craniofacial research is favourable because of the similarity of many of the ferret's anatomical, metabolic and physiological features to those of man. Other advantages are cost-effectiveness and possibly less ethical controversy. However, information on the ...

journal_title：Archives of oral biology

authors： He T,Friede H,Kiliaridis S

更新日期：2002-08-01 00:00:00

abstract：:The impeded/unimpeded eruption rates of the rat incisor have been much studied. The most commonly used optical microscopic method, which has inherent weaknesses, was compared here with an image-analysis method to measure the eruption rate of the mandibular incisor. The study also evaluated the incisal edge as a refere...

journal_title：Archives of oral biology

authors： Lee CK,Law KT,King NM,Rabie AB

更新日期：2002-07-01 00:00:00